Intradermal Device Sets New Standard for Regenerative Aesthetics

Intradermal delivery devices have become increasingly sophisticated within the field of aesthetic medicine, responding to the demand for minimally invasive solutions that maximize patient comfort and treatment efficacy. As the industry continues to evolve, providers are seeking devices that elevate clinical outcomes and foster trust through measurable, reproducible results.

MicronJetUSA, Campaign Photo

MicronJet™ by NanoPass Technologies (Ness Ziona, Israel), a device based on micro-electromechanical systems (MEMS) technology, makes achieving these goals possible. The technology leverages a patent-protected, three-hollow pyramid design that boasts unprecedented mechanical stability and structural precision.

“This unique creation allows for perfect insertion at 45 degrees and delivery of any injectable product designed to be administered to the dermis,” reported Dr. Elisabeth Dancey of Medical Aesthetic Group in London, UK. “The depth is precise at 0.6 mm — right into the mid-dermis level — which is impossible to achieve with a standard needle, particularly when up to 200 injections are required for a skin treatment,” she explained. “The silicon-crystal construction means that even after 200 injections they do not blunt, so each injection is the same as the last.”

The device causes no tissue trauma or bruising at the dermal level, she also noted, making it suitable for regular skin treatments.

For her most popular skin rejuvenation treatment, Dr. Dancey begins with a gentle alpha-hydroxy acid peel and then employs the MicronJet to deliver a poly-vitamin, mineral, hyaluronic acid and amino acid mixture, followed by red-light and near red-light therapy and a gentle hydrating cream. “The tiny blebs created by the treatment will have virtually disappeared and the client can return to normal activities,” she shared.

For Shino Bay Aguilera, DO, board-certified dermatologist and dermatologic surgeon at Shino Bay Cosmetic Dermatology & Laser Institute, Fort Lauderdale, Fla., “I primarily use MicronJet to prime the skin with the essential nutrition and growth factors found in autologous platelet-rich plasma and platelet-rich fibrin, creating an optimal environment for regeneration. One of the most overlooked contributors to accelerated skin aging is the exhaustion of both stem cells and aged fibroblasts,” he explained.

“When we prime the skin intradermally with regenerative biomolecules, we’re not just treating the surface — we’re nourishing the very cells responsible for collagen and elastin production. By delivering these actives precisely into the dermis where fibroblasts reside, we awaken and reinvigorate their capacity to repair, regenerate and respond.”

According to Dr. Aguilera, MicronJet, powered by MEMS technology, represents a breakthrough in precise, consistent and virtually painless intradermal delivery. “MicronJet provides the missing link that delivers cellular nutrition where it is needed most, allowing tired cells to thrive and the skin to behave in a more youthful, vigorous way,” he commented. “It’s also highly effective for delivering lidocaine prior to energy-based treatments.”

In addition, shared Dr. Aguilera, cutaneous delivery of neuromodulators using this technology allows for the refined treatment of skin quality concerns such as enlarged pores, acne, facial flushing from rosacea, excess sebum production, sweating, and scar prevention — all with enhanced precision and minimal discomfort.

And in a field where precision, comfort, and results drive patient loyalty, MicronJet is not just a new tool, according to the company — it is the new way to inject.

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